Direct flights from Manchester to Frankfurt take just an hour and three quarters. Morning and early afternoon flights are more readily available, although if you book early enough there should be choices to travel in the evening for a similar price.
There are plenty of direct flights to choose from on the Manchester to Frankfurt route, although if it is necessary to take a connecting service then Vienna is the likeliest candidate for a stopover. The wait shouldn't be much more than an hour and a half at the Austrian capital, but can be as short as 40 minutes.
Frankfurt is a major global financial hub, and its airport is the third busiest in Europe. The airport is located 7.5 miles southwest of Frankfurt’s city centre, and is well-served by ground transportation links.
Frankfurt Airport has two train stations, with one catering for passengers travelling to regional areas and the other for those undertaking long-distance journeys. Tickets and information on local transportation can be obtained at the RMV Mobility Centre or DB Travel Centre in Terminal 1, B Concourse, Level 0.
Plenty of buses operate from Terminal 1 to various locations around Frankfurt, while the number 61 to the Frankfurt South train station, 62 to Schwanheim and AIRliner to Darmstadt also depart from the bus stop at hall E, exit 8 of Terminal 2.
Taxis from the city centre should take between 20-30 minutes, while a number of hotels run shuttle services to the airport that stop in front of both terminals. Alternatively, you will find rental car companies such as Avis, Budget, Enterprise, Europcar, Hertz and Sixt in the arrivals area of Terminals 1 and 2.